Home > Uncategorized > Introduction to Human Anatomy Lecture 23 Notes: Autonomic Drugs 1

Introduction to Human Anatomy Lecture 23 Notes: Autonomic Drugs 1

Overview

Today we have a 40 minute lecture, part 1 of 4, on drugs affecting the autonomic nervous system.  This ought to be an interesting mini-series.

Details

The autonomic nervous system is the “rest and digest system.”

Parasymphatomimetic Drugs – muscarinic cholinergic agonists.  Mimics the effects of parasympathetic molecules on the body.  Agonists active.  Giving acetylcholine directly would have too short of an action time.

epinephrine is adrenalin.

Direct Acting Cholinergic Agonists

Prototype – evosac

pharmacodynamics activates all of the muscocarinic ACl receptor sites.

Pharmacokinetics is what the drug does to the body.

Clinical uses

Used to increase salivation for treatment of xerostomia or sjorgren’s syndrome.

Used to increase G motility to post operation atomy after general anesthesia

Used to increase emptying of the urinary bladder in the urinary bladder.

Decrease intra-ocular pressure in glaucoma.  During times of stress, the pressure in the eye increases.  Chronic increase is glaucoma.

Contraindication is a warning.  Don’t use if you have asthma.  This drug increases the parasympathetic response.  Broncoconstriction is also caused.

Warnings or Cautions are for effects on the entire body.  The drug slows the heart rate.

Can cause headaches, generalized vasociatation or bodily flushing, salivation, hypertension, abdominal cramps with diarrhea, sweating.  bradycardia slowing of the heart rate.

Miosis and cycloplegia – pupilary constriction and eye paralysis on near vision

Cautions – use the drug but you’ll see these sides

Contraindication – don’t use it

Blockage of GIT, rupture or intestine.  Obstruction of the urinary tract.  Ulcers, asthma, heart problems.

Parasympathlytic Drugs

Block ACh sites

belladonna alkaloids

Prototype: atropine sulfate, tropine

Decrease secretions, decreased salivation, dry air passages,

prior to surgery, during surgery and after surgery

colds hayfever

eye examps

increase heart rate

controlling aurethis or bed wetting

produce sedation

motion sickness

irritable bowel syndrome IBS

PK

action terminated by renal excretion

dry as a bone, hot as a hare, red as a beet, blind as a bat

Block the parasympathetic into stress mode

Atrovant for asthma

block the parasympathetic, dilate airways.

Review

Utility pole: subtransmission line/distribution line

Electronegativity: NOF Cl Kr

Flip Flops: SR, JK, D, T

Z = R + jX,

H = (4 * Pi * #Turns * #Turns * coil Area * mu) / (coil Length * 10,000,000)

<br /><br /><br /><br /><br /><br /><br /><br /><br />
frac{V_text{s}}{V_{text{p}}} = frac{N_text{s}}{N_text{p}}<br /><br /><br /><br /><br /><br /><br /><br /><br />
” /></p><br /><br /><br /><br /><br /><br /><br />
<p>Thyristor/SCR – gate, anode, cathode, one direction</p><br /><br /><br /><br /><br /><br /><br />
<p>Triac – bidirectional</p><br /><br /><br /><br /><br /><br /><br />
<p>Hardware random number generator: Transducer, amplifier, ADC</p><br /><br /><br /><br /><br /><br /><br />
<p>Power conversion:</p><br /><br /><br /><br /><br /><br /><br />
<p>The power conversion systems can be classified according to the type of the input and output power</p><br /><br /><br /><br /><br /><br /><br />
<ul><br /><br /><br /><br /><br /><br /><br />
<li>AC to DC (<a title=” />rectifier)</p><br /><br /><br /><br /><br />
<ul><br /><br /><br /><br /><br />
<li>DC to AC (<a title=” />inverter)</p><br /><br /><br /><br />
<ul><br /><br /><br /><br />
<li>DC to DC (<a title=” />DC-to-DC converter)</p><br /><br /><br />
<ul><br /><br /><br />
<li>AC to AC (<a title=” />AC-to-AC converter)</p><br /><br />
<table cellspacing=” />MDS The minimum discernible signalCapacitors store electric field, C=Q/V, Xc = 1/2piFC, C = EA/d, V = Qd/EA, E = 0.5CV2<img src=” /></p>
<p>MDS The minimum discernible signal</p>
<p>Capacitors store electric field, C=Q/V, Xc = 1/2piFC, C = EA/d, V = Qd/EA, E = 0.5CV2</p>
<p><img src=

Advertisements
  1. No comments yet.
  1. No trackbacks yet.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: